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Do not crush the contents into the food. Esomeprazole works best if taken on an empty stomach at least one hour before a meal. Take your doses at regular intervals. Do not take your medicine more often than directed.<br /> <br /> Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.<br /> <h3><u>What if I miss a dose?</u></h3><br /> If you miss a dose, just take your next scheduled dose when it is due. Do not use double or extra doses.<br /> <h3><u>What drug(s) may interact with esomeprazole?</u></h3><br /> • ampicillin<br /> • diazepam<br /> • digoxin<br /> • iron salts<br /> • itraconazole, ketoconazole, voriconazole, or other prescription medicines for fungus or yeast infections<br /> • phenytoin<br /> • warfarin<br /> <br /> Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.<br /> <h3><u>What side effects may I notice from taking esomeprazole?</u></h3><br /> <p><h4> Side effects that you should report to your prescriber or health care professional as soon as possible:</h4></p> • chest pain or tightness<br /> • dark yellow or brown urine<br /> • shortness of breath<br /> • skin rash<br /> • unusual tiredness or fatigue<br /> <br /> <p><h4> Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):</h4></p> • headache<br /> • diarrhea or constipation<br /> • flatulence (gas)<br /> • nausea/vomiting<br /> • dry mouth<br /> <h3><u>What should I watch for while taking esomeprazole?</u></h3><br /> It can take several days of therapy with esomeprazole before your stomach pains improve. 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